Croscarmellose Sodium (CCS) is a super disintegrant and dissolution aid for use in solid dosage formulations with high absorption capacity. It is produced from high purity dissolving non-GMO wood pulp and contains no starch or sugars.
Grades: CROSSCARMELLOSE SODIUM (BP /IP/ USP/ NF)
Pharmellose® is cross-linked carboxy methyl cellulose sodium. It is a white, free flowing powder.
Pharmellose® is used as disintergrant in tablets, capsules and granules.
In capsules, Pharmellose® suggested use level is 10-25%
Pharmellose® as a tablet disintegrant, it may be used at concentration of up to 5%, although a use level of 2% w/w is recommended for tablets prepared by direct compression and 3% w/w, for tablets prepared by wet granulation.
Pharmellose® is suitable for a variety of tablet and capsule formulations.
Pharmellose® is effective in combination with both insoluble filler-binders, such as Micro crystaline Cellulose(MCC) and dicalcium phosphate and slightly soluble to soluble filler binders such as mannitol and lactose at concentrations of 2-6%.
Pharmellose® is effective when used as intra-granular or extra-granular super disintegrant, or when divided between these locations.
FDA License available in IP/ BP /USP/ NF/EP
DMF Available
Can be used in both Wet Granulation & Direct Compression
Superior Table Disintegrator
Effective at low use levels
Superior Long Term Dissolution Stability
Insensitive to Tablet Hardness
Use as food additive
Use in Soaps, cosmetics, detergents etc.
Lubricants, softening and release agents
Stearic acid is used as a negative plate additive in the manufacture of lead-acid batteries.
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NITIKA PHARMACEUTICAL SPECIALITIES PVT. LTD. (NITIKA CHEMICALS) was found in 1991 as a small manufacturing unit has grown today into a dynamic production center for range of products finding applications in various Industry Verticals.
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